# Cardiovascular diseases-a guide #
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Ang presyon ng dugo ay isa sa mga pangunahing indikasyon ng kalusugan, na hindi lamang sumasalamin sa puso at sistema ng sirkulasyon, kundi pati na rin sa aktibidad ng mga bato, mga organo ng endokrin, paggawa ng dugo, at ng sistema ng nerbiyos. Kaya naman, walang isang unibersal na gamot laban sa mataas na presyon ng dugo. Hindi ka basta basta puwedeng pumunta sa botika at magtanong ng 'tableta para sa presyon,' kasi agad na tatanungin ng parmasyutiko – anong gamot ang nireseta sa iyo ng doktor? <a href="https://doc.neutrinet.be/s/fUPyeotaP0">PUMUNTA SA WEBSITE>>> </a>
Cardiovascular diseases — a guide
Introduction
Cardiovascular diseases (CVD) are one of the leading causes of death worldwide. According to the world health organization (WHO), every year approximately 17.9 million deaths, equivalent to approximately 32% of all deaths worldwide. These diseases include a variety of diseases of the heart and blood vessels, including Coronary heart disease (CHD), congestive heart failure, stroke, high blood pressure (hypertension) and peripheral arterial disease.
The main forms of cardiovascular disease
Among the most common forms of CVD:
Coronary heart disease (CHD): it is caused by a narrowing of the coronary arteries, usually as a result of atherosclerosis. This can lead to Angina or a heart attack.
High blood pressure (hypertension): A permanently elevated blood pressure (≥140/90 mmHg) charged to the heart and blood vessels and increases the risk for heart attack and stroke.
Congestive heart failure: The heart loses its pumpability, whereby the body is not sufficiently supplied with oxygen.
Stroke (apoplexy): An interruption of the blood supply to the brain, which can lead to permanent damage or death.
Arrhythmias: heart rhythm disorders, ranging from harmless to life-threatening forms.
Risk factors
The main risk factors for CVD in modifiable and non-modifiable sub-parts:
Modifiable Factors:
Smoking
Overweight and obesity
Lack of exercise
Unhealthy diet (high, high in salt, fat and sugar content)
Alcohol consumption
Stress
Diabetes mellitus
Hyperlipidemia (elevated blood fats)
Non-modifiable factors:
Age (the risk increases with age)
Gender (men are up to 50. Age more affected; after Menopause, the risk of approaching women and the men)
Genetic predisposition and family history
Prevention and lifestyle changes
Effective prevention of CVD is based on a Change of lifestyle:
Regular physical activity: at Least 150 minutes of moderate load per week (e.g., walking, Cycling, Swimming).
Healthy diet: Increased consumption of fruits, vegetables, whole grain products, nuts and low-fat dairy products. Reduction of saturated fats, TRANS fats, salt (<5 g per day) and sugar.
Smoking quitting Smoking: Stop The risk of heart attacks and stroke, reduces seizures significantly.
Alcohol reduction: a Maximum of 10 g of pure alcohol per day for men and 20 g for men.
Weight control: A healthy body mass index (BMI between 18.5 and 24.9 kg/m
2
) reduces the pollution potential for the heart and circulatory system.
Stress management: methods, such as Meditation, Yoga or progressive muscle relaxation can help reduce Stress.
Diagnosis and treatment
The diagnosis of CVD includes:
History and physical examination
Blood pressure measurement
Laboratory Tests (Lipid Spectrum Of Blood Sugar, Kidney Values)
Electrocardiogram (ECG)
Echocardiography (ultrasound of the heart)
Load tests (e.g., treadmill test)
Coronary angiography for suspected CHD
The treatment depends on the particular disease and can include medication, as well as operational measures:
Medications: antihypertensives, statins, anticoagulants, beta-blockers, ACE‑inhibitors, etc.
Interventional procedure: PTCA (balloon dilatation), stent implantation
Surgery: Bypass Surgery, Heart Valve Replacement
Conclusion
Cardiovascular diseases represent a serious health challenge. Through a consistent prevention, early diagnosis and adequate treatment of many disease, but cases and deaths prevented. A healthy lifestyle is the most important component to the reduction of individual risk.
## Cardiovascular disease who ##
Cardiovascular diseases: the role of The world health organization (WHO)
Cardiovascular diseases (HKK) is worldwide the leading cause of death and are associated with significant socio-economic costs. According to the latest data from the world health organization (WHO) die each year, approximately 17.9 million people to the consequences of cardiovascular disease, nearly 32 % of all deaths worldwide. More than 75% in low - and middle-developed countries.
Definition and main forms
Heart disease refers to a group of diseases that affect the heart and blood vessels. Among the most important forms:
Coronary heart disease (CHD),
Stroke (Apoplexy),
Heart failure,
arrhythmic heart disease,
High Blood Pressure (Hypertension),
peripheral arterial occlusive disease.
Risk factors according to the WHO Definition
The WHO has identified a number of modifiable and non-modifiable risk factors:
Modifiable Factors:
unhealthy diet (high in salt, sugar and fat content),
lack of physical activity,
Tobacco,
excessive consumption of alcohol,
Overweight and obesity,
increased blood pressure,
elevated blood fat levels (dyslipidemia),
increased blood sugar level (Diabetes mellitus).
Non-modifiable factors:
Age
Gender (men are up to 50. Age at greater risk),
family history.
Strategies of the WHO for the prevention
The WHO has developed a number of global initiatives for the reduction of cardiovascular diseases. The Central objective of the Global non-communicable diseases action plan 2025 is to reduce premature deaths from non-communicable diseases (including HKK) to 25%.
These include measures such as:
Introduction of salt-reduction programmes,
Ban on industrially produced trans-fatty acids,
Increased taxes on sugary drinks and tobacco,
The promotion of physical activity in cities and schools,
Building health systems for early detection and treatment of hypertension and Diabetes.
Conclusion
Cardiovascular diseases remain one of the biggest health challenges of the present. The WHO plays a Central role in the coordination of international efforts to combat these diseases. Through evidence-based prevention strategies, global agreements and the support of health systems in developing countries, the burden of heart and circulatory diseases in the world are sustainably reduced.
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## Tablets from hypertension 2 degrees ##
Tablets in hypertension 2. Grade: Pharmacological approaches and clinical recommendations
High blood pressure (arterial hypertension) 2. Degree represents a significant health burden and is characterized by a systolic blood pressure of 160-179 mmHg and a diastolic of 100-109 mmHg. These blood pressure values are associated with an increased risk for cardiovascular events such as heart attack, stroke, and kidney damage. Drug therapy plays in this disease stage, a Central role is usually performed with tablets of different drug classes.
Recommended Drug Classes
According to current guidelines (e.g., the German hypertension League and the European Society of Cardiology), the following drug groups as the first choice in hypertension 2. Recommended grade:
ACE inhibitors (e.g., Enalapril, Ramipril): they inhibit the Angiotensin‑converting enzyme, which leads to vasodilation and thus to a Lowering of peripheral vascular resistance.
AT1‑receptor blocker (so-called Sartans; e.g., Losartan, Valsartan): they block the action of Angiotensin II to the AT1‑receptors, which also leads to a reduction in blood pressure and is often better tolerated than ACE inhibitors.
Calcium channel blockers (e.g., amlodipine, nifedipine): you reduce the Calcium influx into the smooth muscles of the blood vessels, which leads to Relaxation and widening of the blood vessels.
Thiazide diuretics (e.g. hydrochlorothiazide): they promote the excretion of water and salt through the kidneys, which reduces the blood volume and lowers blood pressure.
Beta-blockers (e.g., Metoprolol, Bisoprolol): decrease the heart rate and cardiac output, particularly in patients with additional heart problems (eg, heart failure) are an advantage.
Therapy approach
In practice, treatment often begins with a monotherapy (single drug). In case of inadequate control of blood pressure with a combination therapy of two or more agents is recommended. Frequent and evidence-based combinations are:
ACE inhibitor + calcium antagonist;
AT1‑receptor blocker + thiazide diuretic;
Calcium Antagonist + Thiazide Diuretic.
Customization
Dieußehend of the guidelines, the Medication should be adjusted individually. Here, the following factors play a role:
Present concomitant diseases (Diabetes mellitus, kidney disease, congestive heart failure);
Side-effect profile of the agents (e.g., cough with ACE inhibitors, Edema with calcium antagonists);
Age and gender of the patient;
The cost and availability of the drugs.
Goals of therapy
The primary goal of drug treatment is to keep the blood pressure in the long term under 140/90 mmHg (in the case of elderly patients, if necessary, under 150/90 mmHg). This significantly reduces the risk for organ damage and cardiovascular complications. Regular checks of blood pressure and close coordination with the treating doctor are essential.
Conclusion
Tablets for the treatment of hypertension 2. Degrees are an effective and evidence-based resources to reduce blood pressure and risk reduction. A careful selection of active ingredients, the consideration of individual patient factors and a possible combination therapy to allow for optimal blood pressure control, and contribute significantly to the improvement of the quality of life and life expectancy.